Technology

• Which sequencing technology is used?

  We utilize a sequencing technique called 16s rRNA sequencing. Using PCR, we sequence the v4 region of the 16s gene found in bacteria. The DNA sequences are then matched against a curated bacterial database containing millions of DNA sequences. We are able to identify most bacterial organisms at t...

• Why was 16s sequencing chosen over shallow shotgun, deep shotgun and metatranscriptomics?

  16s rRNA sequencing was chosen as it allows us to tap into thousands of gut microbiome research publications. While we do build our own analytical models to gain insights from our customers' data, we also rely heavily on the research conducted over the last 20 years. 16s rRNA continues to be the ...

• How does Biomesight compare to others gut microbiome tests on the market, e.g. Viome, uBiome, ThryveInside, AtlasBiomed, DayTwo, British Gut Project, American Gut

  Biomesight uses the same sequencing technology used by ThryveInside, AtlasBiomed as well as the not for profit research projects American and British Gut projects. For details of how we differ from DayTwo and Viome, please refer to Why was 16s sequencing chosen over shallow shotgun, deep shotgun...